Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.78 |
| ▸ | TUBB | P07437 | 4/20 | 0.78 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.78 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.78 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.78 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.78 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.78 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.78 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.78 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.78 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.78 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.78 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.78 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.78 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.78 |
| ▸ | NQO2 | P16083 | 2/20 | 0.75 |
| ▸ | NQO1 | P15559 | 1/20 | 0.75 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18889670 | 1.00 | TUBB4A (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4996295 | 0.92 | TUBB1 (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4996285 | 0.92 | TUBB1 (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18889659 | 0.91 | TUBB4A (0.80) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12507433 | 0.90 | RECQL (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4996892 | 0.90 | RECQL (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4996875 | 0.90 | RECQL (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL17141349 | 0.90 | TUBB4A (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5191750 | 0.90 | TUBB4A (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4996948 | 0.89 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708310-B2 | Phenanthroindolizidine and phenanthroquinolizidine alkaloid having a hydroxyl group on the phenanthrene ring thereof, preparation method and use thereof | CHINA MEDICAL UNIVERSITY (TW) | 2017-07-18 | — | — | US | disclosed |
| US-20170152257-A1 | PHENANTHROINDOLIZIDINE AND PHENANTHROQUINOLIZIDINE ALKALOID HAVING A HYDROXYL GROUP ON THE PHENANTHRENE RING THEREOF, PREPARATION METHOD AND USE THEREOF | CHINA MEDICAL UNIVERSITY (TW) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152257-A1 | PHENANTHROINDOLIZIDINE AND PHENANTHROQUINOLIZIDINE ALKALOID HAVING A HYDROXYL GROUP ON THE PHENANTHRENE RING THEREOF, PREPARATION METHOD AND USE THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PAH, HIPK4 | TUBB4A 1313/4885TUBB 2111/4885TUBA3C 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.