Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | NPM1 | P06748 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | USP14 | P54578 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22841435 | 0.89 | KDM4E (0.46) | MAPTHTTALDH1A1HPGDLMNA | |
| SCHEMBL24578600 | 0.82 | RORC (0.35) | HDAC6MAPTHTTALDH1A1LMNA | |
| SCHEMBL21913072 | 0.78 | TSHR (0.50) | MAPTHTTALDH1A1HPGDLMNA | |
| SCHEMBL23799240 | 0.76 | KDM4E (0.41) | MAPTALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL17906201 | 0.75 | KDM4E (0.44) | HDAC6MAPTHTTALDH1A1HPGD | |
| SCHEMBL19270494 | 0.74 | KDM4E (0.35) | HDAC6NPM1MAPTHTTALDH1A1 | |
| SCHEMBL20172309 | 0.74 | MEN1 (0.38) | MAPTHTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21416133 | 0.72 | KDM4E (0.50) | MAPTHTTHPGDLMNASMN1; SMN2 | |
| SCHEMBL21913084 | 0.72 | KDM4E (0.50) | MAPTHTTHPGDLMNASMN1; SMN2 | |
| SCHEMBL20035426 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311826-B1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEMICAL LTD (KR) | 2017-05-24 | — | — | EP | disclosed |