Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22841435 | 0.86 | KDM4E (0.46) | KDM4EL3MBTL1ATMPLA2G2AMAPK8 | |
| SCHEMBL21913084 | 0.78 | KDM4E (0.50) | KDM4EL3MBTL1ATMPLA2G2AMAPK8 | |
| SCHEMBL21416133 | 0.78 | KDM4E (0.50) | KDM4EL3MBTL1ATMPLA2G2AMAPK8 | |
| SCHEMBL21289721 | 0.76 | KDM4E (0.52) | KDM4EL3MBTL1ATMPLA2G2AMAPK8 | |
| SCHEMBL18892113 | 0.76 | HDAC6 (0.38) | KDM4EL3MBTL1ATMPLA2G2AMAPK8 | |
| SCHEMBL24578600 | 0.74 | RORC (0.35) | KDM4EL3MBTL1ATMPLA2G2AMAPK8 | |
| SCHEMBL11993610 | 0.74 | KDM4E (0.46) | KDM4EL3MBTL1ATMPLA2G2AMAPK8 | |
| SCHEMBL22099987 | 0.73 | KDM4E (0.52) | KDM4EL3MBTL1ATMPLA2G2AMAPK8 | |
| SCHEMBL25782348 | 0.71 | TSPO (0.40) | KDM4EL3MBTL1ATMPLA2G2AMAPK8 | |
| SCHEMBL19389327 | 0.70 | KDM4E (0.43) | KDM4EL3MBTL1ATMPLA2G2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3546453-B1 | NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING SAME | LG CHEMICAL LTD (KR) | 2021-09-08 | — | — | EP | disclosed |