Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.95 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.95 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.95 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.95 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.95 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | CASP2 | P42575 | 1/20 | 1.00 |
| ▸ | RAD52 | P43351 | 3/20 | 0.95 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.95 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.95 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.95 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.95 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.95 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.95 |
| ▸ | ESR1 | P03372 | 1/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6300556 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5084795 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5092903 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL329731 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL3684318 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL996021 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Cetylpyridinium SCHEMBL4763 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL313837 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL329979 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Cetylpyridinium SCHEMBL3232752 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8083945-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2011-12-27 | — | — | US | claimed |
| US-20100223208-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS, INC. (US) | 2010-09-02 | — | — | US | claimed |
| US-8083945-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-7955416-B2 | Polymerized polymeric fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2011-06-07 | — | — | US | disclosed |
| US-7938968-B2 | storing and dispensing a fluid includes providing a vessel configured for selective dispensing of the fluid therefrom. The vessel contains an ionic liquid therein. The fluid is contacted with the ionic liquid for take-up of the fluid by the ionic liquid. | MATHESON TRI GAS (US) | 2011-05-10 | — | — | US | disclosed |
| US-7896954-B2 | storing and dispensing a fluid includes providing a vessel configured for selective dispensing of the fluid therefrom; The fluid is contacted with the ionic liquid for take-up of the fluid by the ionic liquid | MATHESON TRI-GAS, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-20100223208-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS, INC. (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100140175-A1 | POLYMERIZED POLYMERIC FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS (US) | 2010-06-10 | — | — | US | disclosed |
| WO-2010065770-A2 | POLYMERIZED POLYMERIC FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS (US) | 2010-06-10 | — | — | WO | disclosed |
| US-7670490-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-20090320771-A1 | IONIC LIQUID MEDIUMS FOR HOLDING SOLID PHASE PROCESS GAS PRECURSORS | MATHESON TRI-GAS (US) | 2009-12-31 | — | — | US | disclosed |
| US-7585415-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS (US) | 2009-09-08 | — | — | US | disclosed |
| US-20080210633-A1 | FLUID STORAGE AND PURIFICATION METHOD | MATHESON TRI-GAS, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080211118-A1 | FLUID STORAGE AND DISPENSING APPARATUS | MATHESON TRI-GAS, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| EP-1877153-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | Matheson Tri-Gas (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006110450-A9 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI GAS (US) | 2006-11-23 | — | — | WO | disclosed |
| WO-2006110450-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS (US) | 2006-10-19 | — | — | WO | disclosed |
| US-20060226072-A1 | Fluid storage and purification method and system | MATHESON TRI-GAS | 2006-10-12 | — | — | US | disclosed |
| US-20060226074-A1 | Fluid storage and purification method and system | MATHESON TRI-GAS | 2006-10-12 | — | — | US | disclosed |
| US-20060226073-A1 | Fluid storage and purification method and system | MATHESON TRI-GAS | 2006-10-12 | — | — | US | disclosed |