Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.95 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.95 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.95 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.95 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.95 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | CASP2 | P42575 | 1/20 | 1.00 |
| ▸ | RAD52 | P43351 | 3/20 | 0.95 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.95 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.95 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.95 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.95 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.95 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.95 |
| ▸ | ESR1 | P03372 | 1/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6300556 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5084795 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5092903 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL329731 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL1889303 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL3684318 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL996021 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Cetylpyridinium SCHEMBL4763 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL329979 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Cetylpyridinium SCHEMBL3232752 | 1.00 | KMT2A (1.00) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 746 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117753387-A | Covalent organic framework nanocapsule material and emulsion acceleration polymerization method thereof | 浙江大学 | 2024-03-26 | — | — | CN | claimed |
| US-11549134-B2 | Modified amadoriase and method for producing the same, agent for improving surfactant resistance of amadoriase and composition for measuring HbA1c using the same | KIKKOMAN CORPORATION (JP) | 2023-01-10 | — | — | US | claimed |
| CN-114835856-A | Self-healing gel material for leaking stoppage and preparation method and application thereof | 中国石油天然气集团有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114057615-A | High-temperature-resistant polymerizable antibacterial agent, preparation thereof and application thereof in synthesis of antibacterial polyester | 浙江大学 | 2022-02-18 | — | — | CN | claimed |
| US-20200263228-A1 | MODIFIED AMADORIASE AND METHOD FOR PRODUCING THE SAME, AGENT FOR IMPROVING SURFACTANT RESISTANCE OF AMADORIASE AND COMPOSITION FOR MEASURING HbA1c USING THE SAME | KIKKOMAN CORPORATION (JP) | 2020-08-20 | — | — | US | claimed |
| US-20190350200-A1 | SYNERGISTIC ANTIMICROBIAL COMPOSITIONS | JUBILANT LIFE SCIENCES LIMITED (IN) | 2019-11-21 | — | — | US | claimed |
| EP-3534708-A1 | SYNERGISTIC ANTIMICROBIAL COMPOSITIONS | Jubilant Life Sciences Limited (IN) | 2019-09-11 | — | — | EP | claimed |
| CN-110113942-A | Synergistic antimicrobial compositions | 朱比兰特生命科学有限公司 | 2019-08-09 | — | — | CN | claimed |
| CN-103992426-B | A kind of antibacterial high water-absorbent resin and preparation method thereof | 浙江卫星石化股份有限公司 | 2017-03-29 | — | — | CN | claimed |
| CN-105744836-A | ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT | 吉友联生命科学有限公司 | 2016-07-06 | — | — | CN | claimed |
| WO-2002002675-A1 | FLAME RETARDANT DISPERSIBLE POWDERS ON A WAX, POLYMER, OR ORGANIC CARRIER | PABU SERVICES, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| WO-2001051767-A2 | ADDITION OF SOLIDS TO GENERATE VISCOSITY DOWNHOLE | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2001-07-19 | — | — | WO | claimed |
| US-6051742-A | Process for preparing chlorohydrins | THE DOW CHEMICAL COMPANY (US) | 2000-04-18 | — | — | US | claimed |
| EP-0600659-B1 | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORP (US) | 1997-07-30 | — | — | EP | claimed |
| EP-0600659-A1 | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORPORATION (US) | 1994-06-08 | — | — | EP | claimed |
| US-5304449-A | Toner and developer compositions with pyridinium compounds and tetrasubstituted ammonium salts as charge enhancing additives | XEROX CORPORATION (US) | 1994-04-19 | — | — | US | claimed |
| EP-0278846-B1 | COSMETIC COMPOSITION IN SPRAY OR AEROSOL FORM FOR THE CARE, TREATMENT AND AESTHETICS OF THE HAIR | LABORATOIRE LACHARTRE SOCIETE ANONYME: (FR) | 1992-04-15 | — | — | EP | claimed |
| US-4486392-A | COMPLEXING, PRECIPITATION WITH CATIONIC SURFACTANT, FROTH FLOTATION | KERNFORSCHUNGSZENTRUM KARLSRUHE GMBH (DE) | 1984-12-04 | — | — | US | claimed |
| EP-0004953-B1 | PROCESS AND APPARATUS FOR THE SELECTIVE SEPARATION OF URANIUM FROM ITS ACCOMPANYING METALS AND FOR ITS RECOVERY | Heckmann, Klaus, Prof. Dr. (DE) | 1982-03-03 | — | — | EP | claimed |
| EP-0004953-A2 | Process and apparatus for the selective separation of uranium from its accompanying metals and for its recovery | Heckmann, Klaus, Prof. Dr. (DE) | 1979-10-31 | — | — | EP | claimed |