Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | PLK1 | P53350 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11567291 | 0.94 | THRB (0.48) | THRBGPR84PLK1THRASMN1; SMN2 | |
| SCHEMBL4809226 | 0.93 | MAOA (0.42) | THRBMAOAMAOBSMN1; SMN2HTT | |
| SCHEMBL10692683 | 0.86 | THRB (0.46) | THRBGPR84THRAMAOAMAOB | |
| SCHEMBL10692323 | 0.84 | THRB (0.49) | THRBGPR84THRA | |
| SCHEMBL10689918 | 0.84 | THRB (0.49) | THRBGPR84THRA | |
| SCHEMBL10686669 | 0.84 | THRB (0.49) | THRBGPR84THRA | |
| SCHEMBL10695147 | 0.84 | THRB (0.49) | THRBGPR84THRA | |
| SCHEMBL10691092 | 0.84 | THRB (0.49) | THRBGPR84THRA | |
| SCHEMBL10690286 | 0.84 | THRB (0.49) | THRBGPR84THRA | |
| SCHEMBL10692218 | 0.84 | THRB (0.49) | THRBGPR84THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3032333-B1 | SHRINK MATERIAL AND PATTERN FORMING PROCESS | SHINETSU CHEMICAL CO (JP) | 2017-05-24 | — | — | EP | disclosed |