Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 6/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12118217 | 0.83 | PAOX (0.57) | PAOXKDM4AKDM4CADRA1AEPHX1 | |
| SCHEMBL18932735 | 0.83 | PAOX (0.57) | PAOXKDM4AKDM4CADRA1AEPHX1 | |
| SCHEMBL11303506 | 0.83 | PAOX (0.57) | PAOXKDM4AKDM4CADRA1AEPHX1 | |
| SCHEMBL17735332 | 0.83 | PAOX (0.57) | PAOXKDM4AKDM4CADRA1AEPHX1 | |
| SCHEMBL22954504 | 0.83 | PAOX (0.57) | PAOXKDM4AKDM4CADRA1AEPHX1 | |
| SCHEMBL24812346 | 0.83 | PAOX (0.57) | PAOXKDM4AKDM4CADRA1AEPHX1 | |
| SCHEMBL8300316 | 0.81 | — | — | |
| SCHEMBL7885797 | 0.80 | PAOX (0.56) | PAOXADRA1AMAOAMAOBKDM4E | |
| SCHEMBL23428769 | 0.79 | PAOX (0.44) | PAOXKDM4AKDM4CMAOAMAOB | |
| SCHEMBL9414550 | 0.79 | PAOX (0.64) | PAOXADRA1AMAOAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657079-B2 | Truncated GLP-1 derivatives and their therapeutical use | NOVO NORDISK A/S (DK) | 2017-05-23 | — | — | US | disclosed |