Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 7/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727725 | 0.88 | PAOX (0.79) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL18849112 | 0.87 | ADRA1A (0.59) | PAOXADRA1AALDH1A1PRMT1 | |
| SCHEMBL7922962 | 0.87 | PAOX (0.60) | PAOXADRA1AALDH1A1PRMT1 | |
| SCHEMBL12292278 | 0.85 | PAOX (0.58) | PAOXMAOAMAOBADRA1AKDM4E | |
| SCHEMBL12292305 | 0.85 | PAOX (0.58) | PAOXMAOAMAOBADRA1AKDM4E | |
| SCHEMBL7885797 | 0.84 | PAOX (0.56) | PAOXMAOAMAOBADRA1AKDM4E | |
| SCHEMBL9414616 | 0.83 | PAOX (0.41) | PAOXMAOAMAOBKDM4EMAPK1 | |
| SCHEMBL12155260 | 0.82 | PAOX (0.55) | PAOXMAOAMAOBADRA1AKDM4E | |
| SCHEMBL12155258 | 0.82 | PAOX (0.64) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL23428769 | 0.82 | PAOX (0.44) | PAOXMAOAMAOBKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101407543-A | Labelled glutamine and lysine analogues | NYCOMED AMERSHAM PLC (GB) | 2009-04-15 | — | — | CN | disclosed |
| CN-1309661-A | Labelled glutamine and lysine analogues | NYCOMED AMERSHAM PLC (GB) | 2001-08-22 | — | — | CN | disclosed |
| EP-0629617-A1 | Heteroatom-bearing ligands and metal complexes thereof | BRACCO International B.V. (NL) | 1994-12-21 | — | — | EP | disclosed |