Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 7/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414550 | 0.84 | PAOX (0.64) | PAOXADRA1AMAOAMAOBKDM4E | |
| SCHEMBL27350172 | 0.83 | MAPT (0.42) | PAOXMAOAMAOBKMT2ACASP2 | |
| SCHEMBL16727725 | 0.81 | PAOX (0.79) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL18893444 | 0.80 | PAOX (0.51) | PAOXADRA1AMAOAMAOBKDM4E | |
| SCHEMBL7922962 | 0.80 | PAOX (0.60) | PAOXADRA1AMEN1KMT2AALDH1A1 | |
| SCHEMBL12155258 | 0.79 | PAOX (0.64) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL13438529 | 0.79 | CYP2C19 (0.50) | PAOXMAOAMAOBMEN1KMT2A | |
| SCHEMBL12292305 | 0.78 | PAOX (0.58) | PAOXADRA1AMAOAMAOBKDM4E | |
| SCHEMBL12292278 | 0.78 | PAOX (0.58) | PAOXADRA1AMAOAMAOBKDM4E | |
| SCHEMBL2628452 | 0.78 | PAOX (0.68) | PAOXALDH1A1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077729-A2 | METAL COMPLEXES DERIVATIZED WITH FOLATE FOR USE IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059640-A2 | METAL COMPLEXES DERIVATIZED WITH FOLATE FOR USE IN DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 1999-11-25 | — | — | WO | disclosed |