Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.34 |
| ▸ | CA1 | P00915 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA9 | Q16790 | 5/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12665663 | 1.00 | RPS6KA1 (0.37) | RPS6KA1EPHX2CA12CA1CA2 | |
| SCHEMBL3446339 | 0.91 | EPHX2 (0.38) | RPS6KA1EPHX2CA12CA1CA2 | |
| SCHEMBL12665665 | 0.91 | EPHX2 (0.38) | RPS6KA1EPHX2CA12CA1CA2 | |
| SCHEMBL12831586 | 0.90 | RPS6KA1 (0.37) | RPS6KA1EPHX2CA12CA1CA2 | |
| SCHEMBL3445550 | 0.90 | CA12 (0.44) | RPS6KA1CA12CA1CA2CA9 | |
| SCHEMBL12674063 | 0.89 | CA12 (0.38) | RPS6KA1EPHX2CA12CA1CA2 | |
| SCHEMBL3447009 | 0.89 | MTNR1A (0.41) | RPS6KA1EPHX2CA12CA1CA2 | |
| SCHEMBL469558 | 0.88 | LARS1 (0.39) | RPS6KA1EPHX2 | |
| SCHEMBL469384 | 0.88 | LARS1 (0.39) | RPS6KA1EPHX2 | |
| SCHEMBL13035561 | 0.88 | RPS6KA1 (0.39) | RPS6KA1EPHX2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124597-A1 | BORON CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-26 | — | — | US | disclosed |
| US-20110124597-A1 | BORON CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124597-A1 | BORON CONTAINING SMALL MOLECULES | BCL6B, BCL6, BLVRB | RPS6KA1 2735/4885EPHX2 4556/4885CA12 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.