Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 11/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287676 | 0.92 | CCR1 (0.54) | CCR1CHRM2CCR5TBXA2R | |
| SCHEMBL652906 | 0.78 | CCR1 (0.56) | CCR1CHRM2CCR5TBXA2R | |
| SCHEMBL652907 | 0.78 | CCR1 (0.56) | CCR1CHRM2CCR5TBXA2R | |
| SCHEMBL10288001 | 0.78 | CCR1 (0.56) | CCR1CHRM2CCR5TBXA2R | |
| SCHEMBL18896018 | 0.76 | CCR1 (0.49) | CCR1CHRM2CCR5 | |
| SCHEMBL15478386 | 0.76 | CCR1 (0.46) | CCR1CHRM2CCR5TBXA2R | |
| SCHEMBL13292243 | 0.74 | CCR1 (0.47) | CCR1CHRM2CCR5TBXA2R | |
| SCHEMBL5056433 | 0.72 | TBXA2R (0.60) | TBXA2R | |
| SCHEMBL5056436 | 0.72 | TBXA2R (0.60) | TBXA2R | |
| SCHEMBL9750035 | 0.72 | TBXA2R (0.60) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663537-B2 | Chemokine receptor antagonists and methods of use | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |