Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | RRM1 | P23921 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.54 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.53 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20152116 | 0.96 | DPP7 (0.61) | DPP7USP2RRM1EPHX1GNAI3 | |
| SCHEMBL30542445 | 0.94 | GNAI3 (0.60) | DPP7USP2RRM1EPHX1GNAI3 | |
| SCHEMBL22643752 | 0.94 | GNAI3 (0.60) | DPP7USP2RRM1EPHX1GNAI3 | |
| SCHEMBL14515546 | 0.94 | GNAI3 (0.60) | DPP7USP2RRM1EPHX1GNAI3 | |
| SCHEMBL2482508 | 0.94 | GNAI3 (0.60) | DPP7USP2RRM1EPHX1GNAI3 | |
| SCHEMBL22414705 | 0.92 | USP2 (0.69) | DPP7USP2RRM1EPHX1GNAI3 | |
| SCHEMBL24072868 | 0.92 | DPP7 (0.61) | DPP7USP2RRM1EPHX1GNAI3 | |
| SCHEMBL26133522 | 0.90 | GNAI3 (0.57) | DPP7USP2RRM1EPHX1GNAI3 | |
| SCHEMBL22857535 | 0.90 | GNAI3 (0.56) | DPP7USP2RRM1EPHX1GNAI3 | |
| SCHEMBL24932113 | 0.90 | GNAI3 (0.56) | DPP7USP2RRM1EPHX1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663466-B2 | Aryl dihydropyridinones and piperidinone MGAT2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-30 | — | — | US | disclosed |