Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.60 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.60 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.59 |
| ▸ | RRM1 | P23921 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.57 |
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30542445 | 1.00 | GNAI3 (0.60) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL14515546 | 1.00 | GNAI3 (0.60) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL2482508 | 1.00 | GNAI3 (0.60) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL20152116 | 0.98 | DPP7 (0.61) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL26133522 | 0.96 | GNAI3 (0.57) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL24932113 | 0.96 | GNAI3 (0.56) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL22857535 | 0.96 | GNAI3 (0.56) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL28552798 | 0.96 | GNAI3 (0.56) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL25914708 | 0.94 | GNAI3 (0.55) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL25921497 | 0.94 | GNAI3 (0.55) | GNAI3GNAO1GNAI1DPP7RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200353076-A1 | ANTI-FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES | SUTRO BIOPHARMA, INC. | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200353076-A1 | ANTI-FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES | FOLR2, FOLR1, FCGRT | GNAI3 4605/4885GNAO1 3603/4885GNAI1 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.