Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 10/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 10/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14018981 | 0.86 | NR1H2 (0.55) | PGRNR1H2NR1H3HTTTDP1 | |
| SCHEMBL14018389 | 0.85 | PGR (0.60) | PGRNR1H2NR1H3HTTTDP1 | |
| SCHEMBL8738326 | 0.85 | HTT (0.64) | PGRNR1H2NR1H3HTTTDP1 | |
| SCHEMBL1889975 | 0.84 | NR1H2 (0.46) | PGRNR1H2NR1H3HTTTDP1 | |
| SCHEMBL3669548 | 0.83 | HTT (0.58) | PGRHTTTDP1L3MBTL1 | |
| SCHEMBL14030831 | 0.83 | PTGS1 (0.51) | PGRNR1H2NR1H3HTTTDP1 | |
| SCHEMBL14030890 | 0.83 | PTGS1 (0.51) | PGRNR1H2NR1H3HTTTDP1 | |
| SCHEMBL10950514 | 0.82 | PTGS2 (0.54) | HTTPTGS2 | |
| SCHEMBL19999886 | 0.81 | NR1H2 (0.51) | PGRNR1H2NR1H3HTTTDP1 | |
| SCHEMBL15472492 | 0.81 | PPARG (0.47) | PGRNR1H2NR1H3HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110112135-A1 | Imidazo [1,2-A] Pyridine Compounds | WYETH LLC | 2011-05-12 | — | — | US | disclosed |
| EP-2231660-A1 | IMIDAZO [1,2-A] PYRIDINE COMPOUNDS | Wyeth LLC (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009086123-A1 | IMIDAZO [1,2-A] PYRIDINE COMPOUNDS | WYETH (US) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112135-A1 | Imidazo [1,2-A] Pyridine Compounds | NR1H2, NR1H3, NR1H4 | PGR 126/4885NR1H2 1/4885NR1H3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.