Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19024738 | 0.85 | PRSS1 (0.53) | ADRB2ADRB1ADRB3ALOX5MAPT | |
| SCHEMBL19024778 | 0.85 | PRSS1 (0.53) | ADRB2ADRB1ADRB3ALOX5MAPT | |
| SCHEMBL19024749 | 0.85 | PRSS1 (0.53) | ADRB2ADRB1ADRB3ALOX5MAPT | |
| SCHEMBL19024788 | 0.85 | PRSS1 (0.53) | ADRB2ADRB1ADRB3ALOX5MAPT | |
| SCHEMBL19024838 | 0.85 | PRSS1 (0.53) | ADRB2ADRB1ADRB3ALOX5MAPT | |
| SCHEMBL19024659 | 0.85 | PRSS1 (0.53) | ADRB2ADRB1ADRB3ALOX5MAPT | |
| SCHEMBL19024922 | 0.85 | CYP3A4 (0.67) | SMN1; SMN2MAPK1ADRB2ADRB1ADRB3 | |
| SCHEMBL19024798 | 0.84 | CYP3A4 (0.54) | ADRB2ADRB1ADRB3ALOX5MAPT | |
| SCHEMBL25778290 | 0.81 | CYP3A4 (0.69) | MAPK1ADRB2ADRB1ADRB3ALOX5 | |
| SCHEMBL406382 | 0.81 | ALOX5 (0.59) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9078864-B2 | Agonists for antimicrobial peptide systems | AKTHELIA PHARMACEUTICALS (IS) | 2015-07-14 | — | — | US | disclosed |
| US-20110118217-A1 | Agonists for Antimicrobial Peptide Systems | AKTHELIA PHARMACEUTICALS (IS) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118217-A1 | Agonists for Antimicrobial Peptide Systems | VIP, GLP1R, MAVS | SMN1; SMN2 3320/4885HDAC3 2322/4885MAPK1 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.