Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIP | O00170 | 1/20 | 0.46 |
| ▸ | SGTA | O43765 | 1/20 | 0.46 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.46 |
| ▸ | STIP1 | P31948 | 1/20 | 0.46 |
| ▸ | PPP5C | P53041 | 1/20 | 0.46 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.46 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.46 |
| ▸ | TOMM34 | Q15785 | 1/20 | 0.46 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.46 |
| ▸ | AIPL1 | Q9NZN9 | 1/20 | 0.46 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006092 | 0.82 | ALDH1A1 (0.54) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL3453384 | 0.82 | LMNA (0.64) | GRM1ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL1009791 | 0.82 | AIP (0.52) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL1008434 | 0.79 | LMNA (0.46) | GRM1ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL3452222 | 0.73 | GRM1 (0.54) | GRM1ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL1008097 | 0.73 | LMNA (0.43) | GRM1ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL3452732 | 0.73 | SMN1; SMN2 (0.73) | GRM1ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL1007833 | 0.72 | GRIN2C (0.46) | GRM1ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL1006991 | 0.72 | MAPT (0.44) | GRM1ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL13108879 | 0.71 | GRM1 (0.68) | GRM1ALDH1A1HPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | GRIN1, GRM1, GRIK1 | AIP 1031/4885SGTA 1355/4885TOMM70 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.