Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955160 | 0.87 | LMNA (0.38) | LMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL6437172 | 0.83 | LMNA (0.44) | LMNAL3MBTL1TDP1THRBALDH1A1 | |
| SCHEMBL5822752 | 0.77 | THRB (0.55) | LMNAL3MBTL1TDP1THRBALDH1A1 | |
| SCHEMBL11040683 | 0.76 | THRB (0.53) | LMNATDP1THRBALDH1A1 | |
| SCHEMBL19738979 | 0.76 | THRB (0.53) | LMNATDP1THRBALDH1A1 | |
| SCHEMBL428320 | 0.76 | TSHR (0.47) | LMNATHRBALDH1A1 | |
| SCHEMBL29093233 | 0.76 | TSHR (0.47) | LMNATHRBALDH1A1 | |
| SCHEMBL29093054 | 0.76 | TSHR (0.47) | LMNATHRBALDH1A1 | |
| SCHEMBL619867 | 0.76 | TSHR (0.47) | LMNATHRBALDH1A1 | |
| SCHEMBL3885660 | 0.76 | TSHR (0.47) | LMNATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663820-B2 | Recombinase polymerase amplification | ALERE SAN DIEGO INC. (US) | 2017-05-30 | — | — | US | disclosed |