Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387220 | 0.76 | EPHX1 (0.39) | — | |
| SCHEMBL21166211 | 0.76 | MITF (0.35) | MDM2 | |
| SCHEMBL25692698 | 0.74 | EPHX1 (0.36) | — | |
| SCHEMBL17827389 | 0.73 | MDM2 (0.41) | MDM2 | |
| SCHEMBL19570444 | 0.71 | GAA (0.30) | — | |
| SCHEMBL21564930 | 0.70 | GAA (0.37) | — | |
| SCHEMBL18684792 | 0.68 | GAA (0.43) | MDM2 | |
| SCHEMBL104716 | 0.68 | — | — | |
| SCHEMBL104342 | 0.68 | — | — | |
| SCHEMBL21660390 | 0.68 | EPHX1 (0.31) | MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9662311-B2 | Substituted bicyclic compounds as bromodomain inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2017-05-30 | — | — | US | disclosed |