Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17861559 | 0.90 | PGR (0.40) | PGRALDH1A1 | |
| SCHEMBL18898417 | 0.88 | PGR (0.39) | PGRHTT | |
| SCHEMBL17841289 | 0.83 | PGR (0.43) | PGRALDH1A1HPGDHTT | |
| SCHEMBL17857556 | 0.82 | PGR (0.42) | PGRHTT | |
| SCHEMBL16322048 | 0.77 | HTT (0.53) | PGRHTT | |
| SCHEMBL16322050 | 0.77 | HTT (0.53) | PGRHTT | |
| SCHEMBL16321357 | 0.71 | SMN1; SMN2 (0.50) | ALDH1A1MEN1GAAHTTKMT2A | |
| SCHEMBL16321359 | 0.71 | SMN1; SMN2 (0.50) | ALDH1A1MEN1GAAHTTKMT2A | |
| SCHEMBL16321035 | 0.69 | HTT (0.54) | PGRHTT | |
| SCHEMBL16321033 | 0.69 | HTT (0.54) | PGRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663516-B2 | Bicyclic-pyrimidinedione compounds | MyoKardia, Inc. (US) | 2017-05-30 | — | — | US | disclosed |