SCHEMBL18900710

SCHEMBL18900710

Cc1ccc2c3c(oc2c1)C=CCC3

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.37
DRD2 P14416 3/20 0.36
DRD4 P21917 3/20 0.36
DRD3 P35462 2/20 0.36
HPGD P15428 2/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
CDC25A P30304 1/20 0.35
CDC25C P30307 1/20 0.35
RAB9A P51151 3/20 0.33
NPC1 O15118 3/20 0.33
KMT2A Q03164 5/20 0.32
MEN1 O00255 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
POLB P06746 2/20 0.31
MAPT P10636 1/20 0.31
NOS1 P29475 1/20 0.30
PSMB8 P28062 1/20 0.30
KEAP1 Q14145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13086490 0.87 MAPT (0.36) HPGDALDH1A1RAB9ANPC1KMT2A
SCHEMBL24676096 0.84 MAOB (0.31) MAOB
SCHEMBL21253839 0.79 MAOB (0.35) MAOBHPGDALDH1A1RAB9ANPC1
SCHEMBL450881 0.78 KDM4E (0.38) HPGDALDH1A1GAARAB9ANPC1
SCHEMBL21574926 0.77 KDM4E (0.31) HPGDALDH1A1GAA
SCHEMBL18714077 0.76 MAPT (0.40) MAOBHPGDALDH1A1RAB9ANPC1
SCHEMBL12419244 0.74 ALDH1A1 (0.32) MAOBHPGDALDH1A1MAPT
SCHEMBL18789367 0.74 PRKDC (0.35)
SCHEMBL13452001 0.74 MAOB (0.37) MAOBDRD2DRD4DRD3HPGD
SCHEMBL12072344 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174115-A1 CHARGE TRANSPORT MATERIAL Nissan Chemical Industries, Ltd. (JP) 2017-05-31 EP disclosed