Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 4/20 | 0.35 |
| ▸ | XRCC6 | P12956 | 1/20 | 0.35 |
| ▸ | XRCC5 | P13010 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12811178 | 0.81 | AHR (0.44) | MAOACYP2D6ACHE | |
| SCHEMBL450881 | 0.81 | KDM4E (0.38) | MAOA | |
| SCHEMBL12072344 | 0.77 | — | — | |
| SCHEMBL23626413 | 0.76 | L3MBTL1 (0.41) | PRKDCXRCC6XRCC5 | |
| SCHEMBL12811307 | 0.76 | MAOA (0.39) | MAOACYP2D6 | |
| SCHEMBL23285438 | 0.75 | PRKDC (0.38) | PRKDCXRCC6XRCC5MAOABCHE | |
| SCHEMBL22132240 | 0.75 | ALDH1A1 (0.32) | CYP2D6SLC6A2ACHE | |
| SCHEMBL22617758 | 0.75 | — | — | |
| SCHEMBL18900710 | 0.74 | MAOB (0.37) | — | |
| SCHEMBL20999529 | 0.74 | NPC1 (0.46) | HTR6CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017073706-A1 | DIHYDRONAPHTHO[2,3-b]BENZOFURAN DERIVATIVE | 中外製薬株式会社 | 2017-05-04 | — | — | WO | disclosed |