Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18900859 | 0.86 | GPR84 (0.52) | MAPTKMT2AMEN1ALOX15CYP3A4 | |
| SCHEMBL18900946 | 0.85 | GPR84 (0.59) | MAPTKMT2AMEN1AHRGPR84 | |
| SCHEMBL7960283 | 0.85 | CMA1 (0.65) | MAPTKMT2AMEN1AHRALOX15 | |
| SCHEMBL7963792 | 0.83 | CYP1A2 (0.68) | MAPTKMT2AMEN1ALOX15CYP3A4 | |
| SCHEMBL6115415 | 0.83 | CMA1 (0.56) | MAPTKMT2AMEN1AHRALOX15 | |
| SCHEMBL7963656 | 0.79 | POLB (0.48) | MAPTKMT2AMEN1ALOX15CYP3A4 | |
| SCHEMBL18900851 | 0.77 | CMA1 (0.72) | MAPTALOX15CYP3A4RECQLSMN1; SMN2 | |
| SCHEMBL6115861 | 0.77 | AHR (0.45) | MAPTKMT2AMEN1AHRCYP3A4 | |
| SCHEMBL12877772 | 0.76 | TSHR (0.71) | MAPTKMT2AMEN1ALOX15CYP3A4 | |
| SCHEMBL7967791 | 0.76 | CMA1 (0.56) | MAPTKMT2AALOX15CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323991-B1 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2017-05-31 | — | — | EP | disclosed |