Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960283 | 0.88 | CMA1 (0.65) | CMA1TSHRALOX15CYP1A2CYP3A4 | |
| SCHEMBL7951731 | 0.87 | GPR84 (0.56) | CMA1TSHRALOX15S1PR2KMT2A | |
| SCHEMBL18900933 | 0.86 | TSHR (0.55) | CMA1TSHRALOX15CYP1A2CYP3A4 | |
| SCHEMBL6115415 | 0.79 | CMA1 (0.56) | CMA1TSHRALOX15CYP3A4MAPT | |
| SCHEMBL7963792 | 0.79 | CYP1A2 (0.68) | CMA1TSHRALOX15CYP1A2CYP3A4 | |
| SCHEMBL7962204 | 0.79 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL18900944 | 0.76 | MAPT (0.53) | CMA1TSHRALOX15CYP1A2CYP3A4 | |
| SCHEMBL18900946 | 0.75 | GPR84 (0.59) | MAPTSMN1; SMN2KMT2A | |
| SCHEMBL24076925 | 0.75 | ALOX15 (0.70) | CMA1TSHRALOX15RAB9ACYP1A2 | |
| SCHEMBL6115844 | 0.74 | CMA1 (0.63) | CMA1TSHRALOX15RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019417-A2 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-18 | — | — | WO | disclosed |