SCHEMBL1890102

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1894327	0.95	GCK (0.44)	ALOX15MAPK1PDE5APDE4APDE4B
	SCHEMBL12673086	0.93	PDE5A (0.52)	ALOX15MAPK1PDE5APDE4APDE4B
	SCHEMBL1905777	0.86	ALOX15 (0.41)	ALOX15MAPK1PDE5APDE4APDE4B
	SCHEMBL12673203	0.85	PARP1 (0.48)	ALOX15PARP1KCNH2RAB9A
	SCHEMBL12662183	0.85	PDE5A (0.48)	PDE5APDE4APDE4BPDE4CPDE4D
	SCHEMBL12673391	0.85	DHODH (0.46)	PARP1CYP1A2RAB9ANPC1ALDH1A1
	SCHEMBL12662092	0.83	KCNA5 (0.47)	ALOX15MAPK1PARP1ALDH1A1
	SCHEMBL12673323	0.82	ALOX15 (0.48)	ALOX15MAPK1PARP1CYP1A2RAB9A
	SCHEMBL12662186	0.82	CLK2 (0.47)	MAPK1PDE5APDE4APDE4BPDE4C
	SCHEMBL1889694	0.82	PARP1 (0.46)	ALOX15MAPK1PARP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.