Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.35 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.35 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025872 | 0.83 | MEN1 (0.56) | MEN1KMT2AP2RX1TMPRSS4CHRNA7 | |
| SCHEMBL1024009 | 0.75 | MEN1 (0.55) | MEN1KMT2AP2RX1TMPRSS4CHRNA7 | |
| SCHEMBL12955661 | 0.75 | MEN1 (0.48) | MEN1KMT2AP2RX1TMPRSS4CHRNA7 | |
| SCHEMBL1024652 | 0.74 | MEN1 (0.57) | MEN1KMT2AP2RX1TMPRSS4CHRNA7 | |
| SCHEMBL1025021 | 0.73 | TMPRSS4 (0.57) | MEN1KMT2AP2RX1TMPRSS4CHRNA7 | |
| SCHEMBL1027417 | 0.72 | TMPRSS4 (0.56) | MEN1KMT2AP2RX1TMPRSS4CHRNA7 | |
| SCHEMBL1023055 | 0.72 | MEN1 (0.55) | MEN1KMT2AP2RX1TMPRSS4CHRNA7 | |
| SCHEMBL12774911 | 0.70 | BRAF (0.54) | P2RX1TMPRSS4KDRJAK2JAK1 | |
| SCHEMBL1023922 | 0.69 | KCNMA1 (0.65) | MEN1KMT2ATMPRSS4CHRNA7AKT1 | |
| SCHEMBL11993794 | 0.69 | GAA (0.39) | MEN1KMT2AKDM4CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274983-B1 | HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-05-31 | — | — | EP | disclosed |