Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14037081 | 0.74 | LTA4H (0.39) | LTA4HTSHRMAOAKDM1A | |
| SCHEMBL18901014 | 0.70 | TAAR1 (0.36) | DPP4LOXL2TAAR1 | |
| SCHEMBL23473005 | 0.68 | MEN1 (0.37) | — | |
| SCHEMBL21118676 | 0.62 | SLC6A2 (0.38) | MAOB | |
| SCHEMBL18901159 | 0.62 | — | — | |
| SCHEMBL21549610 | 0.61 | MAOB (0.47) | LTA4HTSHRMAOB | |
| SCHEMBL21540141 | 0.61 | LTA4H (0.46) | LTA4HPLA2G2ATSHRMAOAAOC3 | |
| SCHEMBL21755724 | 0.60 | MAOB (0.50) | LTA4HTSHRMAOB | |
| SCHEMBL121432 | 0.60 | ST14 (0.71) | LTA4HPLA2G2ADPP4TSHRLOXL2 | |
| SCHEMBL21547540 | 0.60 | LTA4H (0.39) | LTA4HTSHRMAOAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016951-B1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |