Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | BAX | Q07812 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624036 | 0.80 | KCNA3 (0.42) | LTA4HMAOAMAPT | |
| SCHEMBL12825534 | 0.71 | — | — | |
| SCHEMBL10942010 | 0.68 | LTA4H (0.46) | LTA4HTSHRHTTNR1H2BAX | |
| SCHEMBL12332681 | 0.68 | LTA4H (0.58) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL14649909 | 0.68 | TEAD4 (0.37) | HTTSMN1; SMN2MEN1MAPTCYP2C9 | |
| SCHEMBL7311628 | 0.67 | LTA4H (0.44) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL18654448 | 0.65 | — | — | |
| SCHEMBL19299976 | 0.65 | LTA4H (0.42) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL21305456 | 0.63 | CALM1 (0.39) | LTA4HTSHRNPC1NR1H2MAOA | |
| SCHEMBL22003260 | 0.63 | HPGD (0.41) | TSHRNPC1HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285464-A | Roflumilast intermediate compound and preparation method and application thereof | 山东新时代药业有限公司 | 2023-12-26 | — | — | CN | disclosed |
| EP-3110418-B1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS INC (US) | 2019-11-06 | — | — | EP | disclosed |