Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17790208 | 0.82 | MAPT (0.50) | GAAALDH1A1MAPTAGTR1TDP1 | |
| SCHEMBL19954217 | 0.79 | MAPT (0.44) | GAAALDH1A1MAPTAGTR1TDP1 | |
| SCHEMBL17788643 | 0.78 | MAPT (0.43) | GAAALDH1A1MAPTAGTR1TDP1 | |
| SCHEMBL5868892 | 0.78 | GAA (0.46) | GAAALDH1A1MAPTAGTR1TDP1 | |
| SCHEMBL2096641 | 0.76 | MAPT (0.46) | GAAALDH1A1MAPTAGTR1TDP1 | |
| SCHEMBL10126109 | 0.76 | MAPT (0.50) | GAAALDH1A1MAPTAGTR1TDP1 | |
| SCHEMBL5034243 | 0.76 | MAPT (0.46) | GAAALDH1A1MAPTAGTR1TDP1 | |
| SCHEMBL27596936 | 0.74 | ALDH1A1 (0.48) | GAAALDH1A1MAPTAGTR1TDP1 | |
| SCHEMBL4947113 | 0.74 | SMN1; SMN2 (0.51) | GAAALDH1A1MAPTAGTR1TDP1 | |
| SCHEMBL4941117 | 0.74 | ROCK2 (0.53) | GAAALDH1A1MAPTAGTR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016951-B1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |