Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410100 | 0.84 | RIPK1 (0.34) | RIPK1MTNR1AMTNR1B | |
| SCHEMBL410099 | 0.84 | RIPK1 (0.34) | RIPK1MTNR1AMTNR1B | |
| SCHEMBL10170481 | 0.84 | RIPK1 (0.34) | RIPK1MTNR1AMTNR1B | |
| SCHEMBL405431 | 0.75 | ABCB1 (0.39) | RIPK1MTNR1AMTNR1B | |
| SCHEMBL18793519 | 0.72 | ERN1 (0.33) | RIPK1MTNR1AMTNR1BS1PR1 | |
| SCHEMBL410482 | 0.72 | HDAC6 (0.39) | RIPK1MTNR1AMTNR1B | |
| SCHEMBL410481 | 0.72 | HDAC6 (0.39) | RIPK1MTNR1AMTNR1B | |
| SCHEMBL10170374 | 0.72 | HDAC6 (0.39) | RIPK1MTNR1AMTNR1B | |
| SCHEMBL9968914 | 0.70 | MTNR1A (0.36) | RIPK1MTNR1AMTNR1B | |
| SCHEMBL2772718 | 0.70 | MTNR1A (0.36) | RIPK1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414342-B1 | OXADIAZOLE DERIVATIVES | MERCK SERONO SA (CH) | 2017-05-31 | — | — | EP | disclosed |