Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MVD | P53602 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24242099 | 0.81 | MVD (0.44) | MVDACEALDH1A1 | |
| SCHEMBL14979028 | 0.79 | ACE (0.45) | ACE | |
| SCHEMBL13272263 | 0.79 | ACE (0.45) | ACE | |
| SCHEMBL19658296 | 0.78 | ACE (0.44) | ACE | |
| SCHEMBL18901653 | 0.78 | DPP4 (0.42) | MVDACEL3MBTL1ACE2ALDH1A1 | |
| SCHEMBL8097341 | 0.76 | MVD (0.57) | MVDACEACE2ALDH1A1 | |
| SCHEMBL6786825 | 0.76 | MVD (0.57) | MVDACEACE2ALDH1A1 | |
| SCHEMBL14623965 | 0.74 | DPP4 (0.54) | ACE | |
| SCHEMBL14985781 | 0.74 | DPP4 (0.54) | ACE | |
| SCHEMBL19944791 | 0.74 | DPP4 (0.54) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |