Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.42 |
| ▸ | FAP | Q12884 | 3/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MVD | P53602 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18901477 | 0.78 | MVD (0.41) | ALDH1A1MVDL3MBTL1ACEACE2 | |
| SCHEMBL15024713 | 0.73 | DPP4 (0.54) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL15024857 | 0.70 | ACE (0.49) | DPP4FAPDPP7KDM4EALOX15 | |
| SCHEMBL7019466 | 0.70 | ALDH1A1 (0.40) | DPP4ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL22139321 | 0.69 | HSD17B10 (0.49) | ALDH1A1 | |
| SCHEMBL20256229 | 0.69 | HSD17B10 (0.49) | ALDH1A1 | |
| SCHEMBL25581265 | 0.68 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1 | |
| SCHEMBL23267598 | 0.67 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL12247951 | 0.67 | RAB9A (0.64) | DPP4FAPDPP7ALDH1A1DPP8 | |
| SCHEMBL14188268 | 0.67 | RAB9A (0.64) | DPP4FAPDPP7ALDH1A1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |