Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912601 | 0.75 | ALDH1A1 (0.33) | KMT2AL3MBTL1MEN1 | |
| SCHEMBL18699929 | 0.73 | BTK (0.37) | BTKHSD11B1MAOBKDM1ACTSK | |
| SCHEMBL25554246 | 0.72 | BTK (0.45) | BTKHSD11B1MAOBKDM1ACTSK | |
| SCHEMBL25568447 | 0.72 | BTK (0.45) | BTKHSD11B1MAOBKDM1ACTSK | |
| SCHEMBL21576710 | 0.72 | BTK (0.45) | BTKHSD11B1MAOBKDM1ACTSK | |
| SCHEMBL28545540 | 0.72 | BTK (0.45) | BTKHSD11B1MAOBKDM1ACTSK | |
| SCHEMBL26979888 | 0.72 | BTK (0.45) | BTKHSD11B1MAOBKDM1ACTSK | |
| SCHEMBL25568444 | 0.72 | BTK (0.45) | BTKHSD11B1MAOBKDM1ACTSK | |
| SCHEMBL15542266 | 0.70 | BTK (0.44) | BTKHSD11B1MAOBKDM1ACTSK | |
| SCHEMBL15542263 | 0.70 | BTK (0.44) | BTKHSD11B1MAOBKDM1ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |