Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29681641 | 0.81 | PKM (0.33) | ALDH1A1NPSR1ADAM17SMN1; SMN2CYP4F2 | |
| SCHEMBL4213266 | 0.77 | — | — | |
| SCHEMBL11436553 | 0.77 | — | — | |
| SCHEMBL11850195 | 0.76 | — | — | |
| SCHEMBL18901630 | 0.75 | BTK (0.42) | L3MBTL1MEN1KMT2A | |
| SCHEMBL3153365 | 0.75 | — | — | |
| SCHEMBL1593496 | 0.75 | — | — | |
| SCHEMBL10895051 | 0.74 | TSHR (0.41) | ALDH1A1CYP4F2CYP4A11TSHRTDP1 | |
| SCHEMBL4213264 | 0.73 | — | — | |
| SCHEMBL27564593 | 0.72 | HSD11B1 (0.32) | ALDH1A1ADAM17PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197692-B2 | Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof | WATERS TECHNOLOGIES CORPORATION (US) | 2012-06-12 | — | — | US | disclosed |
| US-20100300972-A1 | POROUS MATERIALS FOR SOLID PHASE EXTRACTION AND CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF | WATERS TECHNOLOGIES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |