Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 19/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.51 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13335014 | 0.91 | CCR2 (0.62) | CCR2KCNH2CCR5FFAR4 | |
| Hydrochloric Acid SCHEMBL3324710 | 0.90 | CCR2 (0.61) | CCR2KCNH2CCR5FFAR4 | |
| Hydrochloric Acid SCHEMBL3326153 | 0.90 | CCR2 (0.61) | CCR2KCNH2CCR5FFAR4 | |
| SCHEMBL13335046 | 0.83 | CCR2 (0.65) | CCR2KCNH2CCR5FFAR4 | |
| Hydrochloric Acid SCHEMBL3324367 | 0.82 | CCR2 (0.64) | CCR2KCNH2CCR5 | |
| SCHEMBL13335034 | 0.81 | CCR2 (0.66) | CCR2KCNH2CCR5FFAR4 | |
| SCHEMBL18901616 | 0.81 | CCR2 (0.60) | CCR2KCNH2CCR5FFAR4 | |
| Hydrochloric Acid SCHEMBL3324564 | 0.81 | CCR2 (0.65) | CCR2KCNH2CCR5FFAR4 | |
| SCHEMBL3025216 | 0.80 | CCR2 (0.70) | CCR2KCNH2CCR5FFAR4 | |
| SCHEMBL18901619 | 0.80 | CCR2 (0.70) | CCR2KCNH2CCR5FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |