Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421482 | 0.89 | EPHX2 (0.52) | EPHX2ADRB1CYP1A2CYP2C19HTR2A | |
| SCHEMBL18902116 | 0.82 | TAAR1 (0.38) | EPHX2HTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL18902025 | 0.81 | MEN1 (0.40) | ADRB1CYP1A2HTR2AHTR2CHTR2B | |
| SCHEMBL18901967 | 0.80 | USP28 (0.46) | HTR2AHTR2CADRB2TAAR1 | |
| SCHEMBL24970139 | 0.76 | EPHX2 (0.56) | EPHX2ADRB1CYP1A2CYP2C19HTR2C | |
| Hydrochloric Acid SCHEMBL31381852 | 0.76 | EPHX2 (0.56) | EPHX2ADRB1CYP1A2CYP2C19HTR2C | |
| SCHEMBL2418069 | 0.76 | EPHX2 (0.56) | EPHX2ADRB1CYP1A2CYP2C19ADRB2 | |
| SCHEMBL7940608 | 0.76 | EPHX2 (0.56) | EPHX2ADRB1CYP1A2CYP2C19HTR2A | |
| Hydrochloric Acid SCHEMBL2365858 | 0.75 | EPHX2 (0.55) | EPHX2ADRB1CYP1A2CYP2C19HTR2A | |
| Hydrochloric Acid SCHEMBL30222993 | 0.75 | EPHX2 (0.55) | EPHX2ADRB1CYP1A2CYP2C19HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173411-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | Purdue Pharma L.P. (US) | 2017-05-31 | — | — | EP | disclosed |