Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755184 | 0.87 | LMNA (0.67) | LMNAGAATSHRKCNA3ALDH1A1 | |
| SCHEMBL12137585 | 0.87 | LMNA (0.67) | LMNAGAATSHRKCNA3ALDH1A1 | |
| SCHEMBL890183 | 0.84 | LMNA (0.50) | LMNAGAATSHRKCNA3ALDH1A1 | |
| SCHEMBL11407476 | 0.84 | LMNA (0.50) | LMNAGAATSHRKCNA3ALDH1A1 | |
| SCHEMBL12174966 | 0.84 | LMNA (0.50) | LMNAGAATSHRKCNA3ALDH1A1 | |
| SCHEMBL12486937 | 0.83 | LMNA (0.71) | LMNAGAATSHRALDH1A1MEN1 | |
| SCHEMBL4418458 | 0.81 | GAA (0.72) | LMNAGAATSHRALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL12487282 | 0.81 | LMNA (0.74) | LMNAGAATSHRALDH1A1MEN1 | |
| SCHEMBL3990860 | 0.81 | GAA (0.72) | LMNAGAATSHRALDH1A1MEN1 | |
| SCHEMBL888844 | 0.81 | LMNA (0.47) | LMNAGAATSHRKCNA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |