Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962230 | 0.83 | KMT2A (0.65) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL16962857 | 0.82 | KMT2A (0.64) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL18902218 | 0.81 | L3MBTL1 (0.46) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL17021999 | 0.78 | KCNH2 (0.75) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL17006311 | 0.78 | KCNH2 (0.75) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL18902175 | 0.75 | KMT2A (0.45) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL18902296 | 0.75 | KMT2A (0.53) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL18902187 | 0.74 | KMT2A (0.52) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL18902113 | 0.72 | KMT2A (0.46) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL19475192 | 0.72 | MAPT (0.66) | KMT2AMAPTMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900674-B1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH | UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-05-31 | — | — | EP | disclosed |