Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17018760 | 0.88 | KMT2A (0.50) | L3MBTL1KMT2AKCNH2MITFMAPT | |
| SCHEMBL17006418 | 0.86 | L3MBTL1 (0.52) | L3MBTL1KMT2AKCNH2MAPTMEN1 | |
| SCHEMBL17018754 | 0.86 | L3MBTL1 (0.50) | L3MBTL1KMT2AKCNH2MITFMAPT | |
| SCHEMBL17006340 | 0.83 | MAPT (0.63) | L3MBTL1KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL17018758 | 0.83 | RAD52 (0.45) | L3MBTL1KMT2AKCNH2MITFMAPT | |
| SCHEMBL18902186 | 0.81 | KMT2A (0.47) | L3MBTL1KMT2AKCNH2MITFMAPT | |
| SCHEMBL17018756 | 0.80 | ALDH1A1 (0.55) | L3MBTL1KMT2AKCNH2MAPTMEN1 | |
| SCHEMBL17021999 | 0.78 | KCNH2 (0.75) | L3MBTL1KMT2AKCNH2MITFMAPT | |
| Hydrochloric Acid SCHEMBL17006311 | 0.77 | KCNH2 (0.75) | L3MBTL1KMT2AKCNH2MITFMAPT | |
| SCHEMBL17018757 | 0.74 | FABP4 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900674-B1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH | UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-05-31 | — | — | EP | disclosed |