Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL3464024 | 0.96 | TRIM24 (0.32) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL30995324 | 0.93 | TRIM24 (0.33) | TRIM24TRIM33ALDH1A1MEN1CYP2C9 | |
| SCHEMBL27197468 | 0.86 | — | — | |
| SCHEMBL30690314 | 0.84 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL6922879 | 0.79 | OR51E2 (0.43) | CRBN | |
| SCHEMBL27323 | 0.76 | — | — | |
| SCHEMBL9941997 | 0.76 | — | — | |
| SCHEMBL1831166 | 0.76 | — | — | |
| SCHEMBL6449501 | 0.74 | — | — | |
| SCHEMBL21752028 | 0.74 | CHRNA7 (0.33) | TRIM24TRIM33ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900674-B1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH | UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-05-31 | — | — | EP | disclosed |