SCHEMBL18902822

SCHEMBL18902822

C1=CCC(c2cc(-c3ccccc3)cc(-c3nc(-c4cccc(-c5ccccn5)c4)nc(-c4cccc(-c5ccccn5)c4)n3)c2)C=C1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.34
TDP1 Q9NUW8 2/20 0.34
SMN1; SMN2 Q16637 5/20 0.34
RAB9A P51151 4/20 0.34
TP53 P04637 4/20 0.34
PKM P14618 3/20 0.34
LMNA P02545 3/20 0.34
MAPT P10636 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
TSHR P16473 2/20 0.34
KLF5 Q13887 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HTR1A P08908 1/20 0.34
HTR7 P34969 1/20 0.34
KAT6A Q92794 1/20 0.33
GRM5 P41594 5/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
PIK3CG P48736 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26499214 0.85 HTR1A (0.39) KDM4ETDP1SMN1; SMN2TP53LMNA
SCHEMBL21889634 0.84 KDM4E (0.31) KDM4ESMN1; SMN2RAB9ATP53PKM
SCHEMBL23966391 0.84 KDM4E (0.30) KDM4ESMN1; SMN2RAB9ATP53PKM
SCHEMBL17449882 0.83 SMN1; SMN2 (0.39) KDM4ETDP1SMN1; SMN2RAB9ATP53
SCHEMBL26790279 0.82 HTR1A (0.31) HTR1AHTR7GRM5
SCHEMBL18644481 0.82 GP6 (0.35) KDM4ELMNAMAPTALDH1A1HPGD
SCHEMBL14949463 0.81 MEN1 (0.33) SMN1; SMN2RAB9AMAPTALDH1A1HPGD
SCHEMBL17932826 0.80 KDM4E (0.52) KDM4ETDP1SMN1; SMN2RAB9ATP53
SCHEMBL15828113 0.80 GRM5 (0.36) KDM4ETDP1SMN1; SMN2RAB9ATP53
SCHEMBL21483710 0.79 KDM4E (0.36) KDM4ETDP1SMN1; SMN2RAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225148-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-20230225148-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
EP-3174121-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2021-11-17 EP disclosed
EP-3219714-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2017-09-20 EP disclosed
EP-3174121-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-05-31 EP disclosed