SCHEMBL18903007

SCHEMBL18903007

Nc1ccc2ccc(-c3ccc4ccccc4c3)cc2c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.77
CYP3A4 P08684 2/20 0.77
HSD17B10 Q99714 2/20 0.77
ALOX15 P16050 1/20 0.74
CASP1 P29466 1/20 0.74
CASP7 P55210 1/20 0.74
HBB P68871 1/20 0.74
HIF1A Q16665 1/20 0.74
TDP1 Q9NUW8 1/20 0.74
ESR1 P03372 2/20 0.54
ESR2 Q92731 2/20 0.54
ALOX5 P09917 1/20 0.52
CYP1A2 P05177 1/20 0.52
HSD17B1 P14061 1/20 0.50
HSD17B2 P37059 1/20 0.50
SRC P12931 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
KDM4E B2RXH2 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13304735 0.98 ALDH1A1 (0.81) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL26834197 0.90 ALDH1A1 (0.68) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL15712427 0.89 ALDH1A1 (0.60) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL6537114 0.88 CYP3A4 (0.65) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL29441264 0.88 CYP3A4 (0.65) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL28528867 0.88 CYP3A4 (0.65) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL28981808 0.88 CYP3A4 (0.65) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
Naphthalene SCHEMBL3939830 0.88 ALDH1A1 (0.89) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
Naphthalene SCHEMBL3935606 0.88 ALDH1A1 (1.00) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
Naphthylamine SCHEMBL76713 0.88 ALDH1A1 (1.00) ALDH1A1CYP3A4HSD17B10ALOX15CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174121-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-05-31 EP disclosed