Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 7/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509524 | 0.74 | SMN1; SMN2 (0.33) | LMNAHTTNMT1L3MBTL1SMN1; SMN2 | |
| SCHEMBL18903780 | 0.70 | NMT1 (0.42) | LMNAHTTMAPTNMT1L3MBTL1 | |
| SCHEMBL16502970 | 0.69 | L3MBTL1 (0.61) | LMNAHTTNMT1L3MBTL1SMN1; SMN2 | |
| SCHEMBL18903920 | 0.69 | MAPT (0.39) | LMNAHTTMAPTNMT1L3MBTL1 | |
| SCHEMBL18904148 | 0.68 | NMT1 (0.40) | LMNAHTTNMT1CRHBPCRHR2 | |
| SCHEMBL16502957 | 0.68 | PDE4D (0.39) | LMNAHTTNMT1L3MBTL1SMN1; SMN2 | |
| SCHEMBL18903990 | 0.68 | NMT1 (0.40) | LMNAHTTMAPTNMT1L3MBTL1 | |
| SCHEMBL18904132 | 0.67 | NMT1 (0.44) | MAPTNMT1 | |
| SCHEMBL18903917 | 0.67 | L3MBTL1 (0.37) | LMNAHTTMAPTNMT1L3MBTL1 | |
| SCHEMBL18904060 | 0.67 | NMT1 (0.41) | LMNAHTTMAPTNMT1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |