Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18904190 | 0.71 | TSHR (0.37) | NMT1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL18903922 | 0.70 | TP53 (0.44) | NMT1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18903785 | 0.68 | LMNA (0.37) | NMT1SMN1; SMN2CRHBPCRHR2LMNA | |
| SCHEMBL18903917 | 0.68 | L3MBTL1 (0.37) | NMT1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18904060 | 0.68 | NMT1 (0.41) | NMT1SMN1; SMN2NR2F2PKMLMNA | |
| SCHEMBL16509495 | 0.66 | FFAR4 (0.60) | NMT1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL18903780 | 0.66 | NMT1 (0.42) | NMT1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL18903979 | 0.65 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1ACHETSHRNPC1 | |
| SCHEMBL16509524 | 0.65 | SMN1; SMN2 (0.33) | NMT1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL16502943 | 0.64 | KMT2A (0.59) | NMT1MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |