Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18903949 | 0.71 | HTT (0.38) | NMT1SMN1; SMN2LMNAHTT | |
| SCHEMBL18904219 | 0.69 | NMT1 (0.55) | NMT1 | |
| SCHEMBL16509621 | 0.68 | NMT1 (0.55) | NMT1SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL18904188 | 0.68 | KMT2A (0.46) | NMT1SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL16502994 | 0.66 | SMN1; SMN2 (0.70) | NMT1SMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL14930167 | 0.66 | TP53 (0.44) | LMNAHTTL3MBTL1 | |
| SCHEMBL13551811 | 0.65 | LMNA (0.39) | LMNAHTT | |
| SCHEMBL18903785 | 0.65 | LMNA (0.37) | NMT1SMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL18903780 | 0.65 | NMT1 (0.42) | NMT1SMN1; SMN2LMNAHTTTSHR | |
| SCHEMBL13554194 | 0.63 | TP53 (0.41) | SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |