Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NMT1 | P30419 | 10/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502976 | 0.90 | LMNA (0.63) | LMNAHTTSMN1; SMN2L3MBTL1NMT1 | |
| SCHEMBL13457978 | 0.89 | LMNA (0.66) | LMNAHTTSMN1; SMN2L3MBTL1NMT1 | |
| SCHEMBL16503034 | 0.87 | SMN1; SMN2 (0.68) | LMNAHTTSMN1; SMN2L3MBTL1NMT1 | |
| SCHEMBL16509593 | 0.84 | LMNA (0.61) | LMNAHTTSMN1; SMN2L3MBTL1NMT1 | |
| SCHEMBL16503036 | 0.79 | LMNA (0.61) | LMNAHTTSMN1; SMN2L3MBTL1NMT1 | |
| SCHEMBL16502941 | 0.79 | LMNA (1.00) | LMNAHTTSMN1; SMN2L3MBTL1NMT1 | |
| SCHEMBL16497565 | 0.79 | LMNA (0.79) | LMNAHTTSMN1; SMN2L3MBTL1NMT1 | |
| SCHEMBL18903979 | 0.78 | SMN1; SMN2 (0.37) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL16503063 | 0.78 | LMNA (0.69) | LMNAHTTSMN1; SMN2L3MBTL1NMT1 | |
| SCHEMBL16509598 | 0.76 | HTT (0.62) | LMNAHTTSMN1; SMN2L3MBTL1NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |