Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 16/20 | 0.48 |
| ▸ | CHKA | P35790 | 2/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868795 | 0.83 | NMT1 (0.70) | NMT1 | |
| SCHEMBL18904150 | 0.74 | NMT1 (0.56) | NMT1 | |
| SCHEMBL18903943 | 0.73 | HRH3 (0.43) | NMT1ALDH1A1 | |
| SCHEMBL18904018 | 0.72 | NMT1 (0.65) | NMT1 | |
| SCHEMBL3264662 | 0.72 | ALDH1A1 (0.45) | NMT1CHKAALDH1A1 | |
| SCHEMBL1852248 | 0.71 | NMT1 (0.69) | NMT1 | |
| SCHEMBL18904173 | 0.68 | NMT1 (0.55) | NMT1 | |
| SCHEMBL18903996 | 0.67 | NMT1 (0.51) | NMT1 | |
| SCHEMBL18904219 | 0.66 | NMT1 (0.55) | NMT1 | |
| SCHEMBL18903862 | 0.66 | NMT1 (0.69) | NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |