Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171511 | 0.79 | CTBP2 (0.52) | CTBP2GAATDP1POLBAPEX1 | |
| SCHEMBL15241380 | 0.78 | CES1 (0.56) | CTBP2GAATDP1ALDH1A1LMNA | |
| SCHEMBL1136835 | 0.76 | CTBP2 (0.49) | CTBP2GAATDP1POLBAPEX1 | |
| SCHEMBL4324709 | 0.76 | GAA (0.53) | CTBP2GAATDP1POLBAPEX1 | |
| SCHEMBL526194 | 0.75 | GAA (0.57) | CTBP2GAATDP1POLBAPEX1 | |
| SCHEMBL105873 | 0.75 | MIF (0.48) | CTBP2GAATDP1POLBAPEX1 | |
| SCHEMBL104746 | 0.73 | CA2 (0.62) | CTBP2GAATDP1POLBAPEX1 | |
| SCHEMBL11185173 | 0.73 | GAA (0.55) | CTBP2GAATDP1POLBAPEX1 | |
| SCHEMBL6562633 | 0.73 | GAA (0.55) | CTBP2GAATDP1POLBAPEX1 | |
| SCHEMBL11578280 | 0.71 | GAA (0.53) | CTBP2GAATDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420498-B1 | 5-substituted quinazolinone derivatives as anti-cancer agents | CELGENE CORP (US) | 2017-05-31 | — | — | EP | disclosed |