Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.63 |
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12158257 | 0.90 | CHRNA7 (0.78) | CHRNA7DHODHIDH2CCNA2CDK2 | |
| SCHEMBL13159797 | 0.89 | CHRNA7 (0.60) | CHRNA7DHODHIDH2CCNA2CDK2 | |
| SCHEMBL13159796 | 0.87 | CHRNA7 (0.55) | CHRNA7DHODHIDH2CYP1A2CCNA2 | |
| SCHEMBL12158245 | 0.86 | CHRNA7 (0.57) | CHRNA7DHODHIDH2CYP1A1CYP1A2 | |
| SCHEMBL12157994 | 0.86 | CHRNA7 (0.58) | CHRNA7DHODHIDH2MPLMEN1 | |
| SCHEMBL12158251 | 0.85 | CHRNA7 (0.55) | CHRNA7DHODHIDH2CYP1A1CYP1A2 | |
| SCHEMBL14707154 | 0.84 | DHODH (0.50) | CHRNA7DHODHMEN1RAB9AKMT2A | |
| SCHEMBL18904287 | 0.84 | KIF11 (0.53) | CHRNA7IDH2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL12158256 | 0.84 | CHRNA7 (0.55) | CHRNA7CYP1A1CYP1A2CYP1B1CCNA2 | |
| SCHEMBL13159765 | 0.82 | CHRNA7 (0.52) | CHRNA7DHODHIDH2CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926719-B1 | 2-ANILINE-4-ARYL SUBSTITUTED THIAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2017-05-31 | — | — | EP | disclosed |