SCHEMBL18904993

SCHEMBL18904993

c1cc(-c2c3ccccc3c(-c3cc4ccccc4c4ccccc34)c3ccccc23)cc(-c2cccc3c2oc2ccccc23)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.52
GGPS1 O95749 1/20 0.45
PTGES2 Q9H7Z7 1/20 0.42
PRKDC P78527 6/20 0.39
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36
CYP11B1 P15538 1/20 0.35
ATM Q13315 1/20 0.35
GAPDH P04406 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17539825 0.99 ALOX5 (0.51) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL15195392 0.96 ALOX5 (0.53) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL15195397 0.95 ALOX5 (0.50) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL24090173 0.95 ALOX5 (0.49) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL15195384 0.92 ALOX5 (0.53) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL15195390 0.92 ALOX5 (0.53) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL15195391 0.92 ALOX5 (0.47) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL27370342 0.92 ALOX5 (0.44) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL10122477 0.91 ALOX5 (0.42) ALOX5GGPS1PTGES2PRKDCALDH1A1
SCHEMBL20127425 0.91 ALOX5 (0.42) ALOX5GGPS1PTGES2PRKDCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210184119-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2021-06-17 US disclosed
US-20170155049-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed
US-20170155049-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed