SCHEMBL20127425

SCHEMBL20127425

c1cc(-c2c3ccccc3c(-c3cc4c5ccccc5oc4c4ccccc34)c3ccccc23)cc(-c2cc3ccccc3c3ccccc23)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.42
CYP11B1 P15538 1/20 0.38
GGPS1 O95749 1/20 0.37
AHR P35869 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.34
MAPT P10636 3/20 0.34
GAPDH P04406 1/20 0.34
DYRK1A Q13627 1/20 0.33
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 4/20 0.33
HPGD P15428 3/20 0.33
TSHR P16473 2/20 0.33
CASP1 P29466 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ALOX15 P16050 1/20 0.33
CASP7 P55210 1/20 0.33
RAB9A P51151 2/20 0.33
MAOB P27338 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10122477 1.00 ALOX5 (0.42) ALOX5CYP11B1GGPS1AHRPTGES2
SCHEMBL24090173 0.91 ALOX5 (0.49) ALOX5CYP11B1GGPS1AHRPTGES2
SCHEMBL18904993 0.91 ALOX5 (0.52) ALOX5CYP11B1GGPS1AHRPTGES2
SCHEMBL17539825 0.90 ALOX5 (0.51) ALOX5CYP11B1GGPS1AHRPTGES2
SCHEMBL20127417 0.90 ALOX5 (0.41) ALOX5CYP11B1AHRMAPTGAPDH
SCHEMBL10122368 0.90 ALOX5 (0.38) ALOX5CYP11B1GGPS1AHRMAPT
SCHEMBL15195392 0.90 ALOX5 (0.53) ALOX5CYP11B1GGPS1AHRPTGES2
SCHEMBL10122468 0.90 ALOX5 (0.41) ALOX5CYP11B1AHRMAPTGAPDH
SCHEMBL10122448 0.89 AHR (0.42) ALOX5CYP11B1AHRMAPTDYRK1A
SCHEMBL10122709 0.89 ALOX5 (0.50) ALOX5GGPS1AHRPTGES2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 ALOX5 4115/4885CYP11B1 483/4885GGPS1 4058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.